The Paleo Solution Part 16

A Novel Therapeutic Target in Inflammatory Uveitis: Transglutaminase 2 Inhibitor. Joonhong Sohn, Ju Byung Chae,2 Sun Young Lee, Soo-Youl Kim, and June Gone Kim. Korean J Ophthalmol. 2010 February; 24(1): 2934.

Intracellular localization and conformational state of transglutaminase 2: implications for cell death. Gundemir S, Johnson GV. PLoS One. 2009 Jul 1;4(7):e6123.

Tissue transglutaminase expression in celiac mucosa: an immunohistochemical study. Gorgun J, Portyanko A, Marakhouski Y, Cherstvoy E. Virchows Arch. 2009 Oct;455(4):363-73. Epub 2009 Sep 12.

Transglutaminases: nature's biological glues. Griffin M, Casadio R, Bergamini CM. Biochem J. 2002 Dec 1;368(Pt 2):377-96.

Serum studies in man after administration of vitamin A acetate and vitamin A alcohol. II. In subjects suffering from disturbances of absorption and digestion. FITZGERALD O, FENNELLY JJ, HINGERTY DJ. Gut. 1962 Mar;3:74-9.

Identification of three wheat globulin genes by screening a Tritic.u.m aestivum BAC genomic library with cDNA from a diabetes-a.s.sociated globulin. Loit E, Melnyk CW, MacFarlane AJ, Scott FW, Altosaar I. BMC Plant Biol. 2009 Jul 17;9:93.

Breath hydrogen and methane responses of men and women to breads made with white flour or whole wheat flours of different particle sizes. Hallfrisch J, Behall KM. J Am Coll Nutr. 1999 Aug;18(4):296-302.

Zonulin upregulation is a.s.sociated with increased gut permeability in subjects with type 1 diabetes and their relatives. Sapone A, de Magistris L, Pietzak M, Clemente MG, Tripathi A, Cucca F, Lampis R, Kryszak D,Carten M, Generoso M, Iafusco D, Prisco F, Laghi F, Riegler G, Carratu R, Counts D, Fasano A. Diabetes. 2006 May;55(5):1443-9.

The gluten connection: the a.s.sociation between schizophrenia and celiac disease. Kalaydjian AE, Eaton W, Cascella N, Fasano A. Acta Psychiatr Scand. 2006 Feb;113(2):82-90.

Dietary gluten and learning to attend to redundant stimuli in rats. Harper DN, Nisbet RH, Siegert RJ. Biol Psychiatry. 1997 Dec 1;42(11):1060-6.

A unifying hypothesis on the development of type 1 diabetes and celiac disease: gluten consumption may be a shared causative factor. Frisk G, Hansson T, Dahlbom I, Tuvemo T. Med Hypotheses. 2008;70(6):1207-9. Epub 2008 Feb 4.

Gluten sensitivity as a neurological illness. Hadjiva.s.siliou M, Grunewald RA, Davies-Jones GA. J Neurol Neurosurg Psychiatry. 2002 May;72(5):560-3.

Headache and CNS white matter abnormalities a.s.sociated with gluten sensitivity. Hadjiva.s.siliou M, Grunewald RA, Lawden M, Davies-Jones GA, Powell T, Smith CM. Neurology. 2001 Feb 13;56(3):385-8.

Gluten sensitivity in multiple sclerosis: experimental myth or clinical truth? Shor DB, Barzilai O, Ram M, Izhaky D, Porat-Katz BS, Chapman J, Blank M, Anaya JM,Shoenfeld Y. Ann N Y Acad Sci. 2009 Sep;1173:343-9.

Gluten sensitivity in j.a.panese patients with adult-onset cerebellar ataxia. Ihara M, Makino F, Sawada H, Mezaki T, Mizutani K, Nakase H, Matsui M, Tomimoto H,Shimohama S.Intern Med. 2006;45(3):135-40. Epub 2006 Mar 1.

Gluten ataxia: pa.s.sive transfer in a mouse model. Boscolo S, Sarich A, Lorenzon A, Pa.s.soni M, Rui V, Stebel M, Sblattero D, Marzari R,Hadjiva.s.siliou M, Tongiorgi E. Ann N Y Acad Sci. 2007 Jun;1107:319-28.

Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics. Hadjiva.s.siliou M, Grunewald R, Sharrack B, Sanders D, Lobo A, Williamson C, Woodroofe N,Wood N, Davies-Jones A. Brain. 2003 Mar;126(Pt 3):685-91.

Clinical, radiological, neurophysiological, and neuropathological characteristics of gluten ataxia. Hadjiva.s.siliou M, Grunewald RA, Chattopadhyay AK, Davies-Jones GA, Gibson A, Jarratt JA,Kandler RH, Lobo A, Powell T, Smith CM. Lancet. 1998 Nov 14;352(9140):1582-5.

Dietary treatment of gluten ataxia. Hadjiva.s.siliou M, Davies-Jones GA, Sanders DS, Grunewald RA. J Neurol Neurosurg Psychiatry. 2003 Sep;74(9):1221-4.

Autoantibodies in gluten ataxia recognize a novel neuronal transglutaminase. Hadjiva.s.siliou M, Aeschlimann P, Strigun A, Sanders DS, Woodroofe N, Aeschlimann D. Ann Neurol. 2008 Sep;64(3):332-43.

Gliadin IgG antibodies and circulating immune complexes. Eisenmann A, Murr C, Fuchs D, Ledochowski M. Scand J Gastroenterol. 2009;44(2):168-71.

Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis. Gori A, Tincati C, Rizzardini G, Torti C, Quirino T, Haarman M, Ben Amor K, van Schaik J,Vriesema A, Knol J, Marchetti G, Welling G, Clerici M. J Clin Microbiol. 2008 Feb;46(2):757-8. Epub 2007 Dec 19.

Excitotoxic neuronal death and the pathogenesis of Huntington's disease. Estrada Sanchez AM, Mejia-Toiber J, Ma.s.sieu L. Arch Med Res. 2008 Apr;39(3):265-76. Pediatrics. 2005 Dec;116(6):e754-9.

Celiac disease: evaluation of the diagnosis and dietary compliance in Canadian children. Rashid M, Cranney A, Zarkadas M, Graham ID, Switzer C, Case S, Molloy M, Warren RE, Burrows V, Butzner JD.

Does rheumatoid arthritis represent an adaptive, thrifty condition? Reser JE, Reser WW. Med Hypotheses. 2010 Jan;74(1):189-94. Epub 2009 Aug 27.

A population-based study of coeliac disease, neurodegenerative and neuroinflammatory diseases. Ludvigsson JF, Olsson T, Ekbom A, Montgomery SM. Aliment Pharmacol Ther. 2007 Jun 1;25(11):1317-27.

Celiac disease. Rubio-Tapia A, Murray JA. Curr Opin Gastroenterol. 2010 Mar;26(2):116-22.

Celiac disease: from gluten to autoimmunity. Briani C, Samaroo D, Alaedini A. Autoimmun Rev. 2008 Sep;7(8):644-50. Epub 2008 Jun 25.

Significance of anti-CCP antibodies in modification of 1987 ACR cla.s.sification criteria in diagnosis of rheumatoid arthritis. Zhao J, Liu X, w.a.n.g Z, Li Z. Clin Rheumatol. 2010 Jan;29(1):33-8. Epub 2009 Oct 15.

Anatomical basis of tolerance and immunity to intestinal antigens. Mowat AM. Nat Rev Immunol. 2003 Apr;3(4):331-41.

Alcohol's role in gastrointestinal tract disorders. Bode C, Bode JC. Alcohol Health Res World. 1997;21(1):76-83.

A type 1 diabetes-related protein from wheat (Tritic.u.m aestivum). cDNA clone of a wheat storage globulin, Glb1, linked to islet damage. MacFarlane AJ, Burghardt KM, Kelly J, Simell T, Simell O, Altosaar I, Scott FW. J Biol Chem. 2003 Jan 3;278(1):54-63. Epub 2002 Oct 29.

Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines. Drago S, El Asmar R, Di Pierro M, Grazia Clemente M, Tripathi A, Sapone A, Thakar M, Iacono G,Carroccio A, D'Agate C, Not T, Zampini L, Cata.s.si C, Fasano A. Scand J Gastroenterol. 2006 Apr;41(4):408-19.

Supportive Versus Immunosuppressive Therapy of Progressive IgA nephropathy (STOP) IgAN trial: rationale and study protocol. Eitner F, Ackermann D, Hilgers RD, Floege J. J Nephrol. 2008 May-Jun;21(3):284-9.

Fats Chapter Seven: Fat: Have a Seat, This May Take a Little While Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice. Merkel M, Velez-Carrasco W, Hudgins LC, Breslow JL. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13294-9. Epub 2001 Oct 23.

Saturated fat consumption in ancestral human diets: implications for contemporary intakes. In: Phytochemicals, Nutrient-Gene Interactions. Cordain L., Meskin MS, Bidlack WR, Randolph RK (Eds.), CRC Press (Taylor & Francis Group), 2006, pp. 115-126.

Dietary fat quality and coronary heart disease prevention: a unified theory based on evolutionary, historical, global and modern perspectives. Ramsden CE, Faurot KR, Carrera-Bastos, P, Sperling LS, de Lorgeril M, Cordain L. Curr Treat Options Cardiovasc Med; 2009;11:289-301.

Fatty acid a.n.a.lysis of wild ruminant tissues: Evolutionary implications for reducing diet-related chronic disease. Cordain L, Watkins BA, Florant GL, Kehler M, Rogers L, Li Y. Eur J Clin Nutr, 2002; 56:181-191.

Fat and Fatty Acid Intake and Metabolic Effects in the Human Body. T.A.B. Sanders Ann Nutr Metab 2009;55:162172.

The Relationship between Dietary Fat and Fatty Acid Intake and Body Weight, Diabetes, and the Metabolic Syndrome. Edward L. Melanson, Arne Astrup,William T. Donahoo. Ann Nutr Metab 2009;55:229243.

Fish-oil supplement has neutral effects on vascular and metabolic function but improves renal function in patients with Type 2 diabetes mellitus. Wong CY, Yiu KH, Li SW, Lee S, Tam S, Lau CP, Tse HF. Diabet Med. 2010 Jan;27(1):54-60.

Efficacy of Omega-3 Fatty Acids in Children and Adults with IgA Nephropathy Is Dosage- and Size-Dependent. Ronald J. Hogg, Lisa Fitzgibbons, Carolyn Atkins, Nancy Nardelli, and R. Curtis Bay; for the North American IgA Nephropathy Study Group. Clin J Am Soc Nephrol 1: 11671172, 2006. doi: 10.2215/CJN.02300606.

Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acid. Clandinin MT, Van Aerde JE, Merkel KL, Harris CL, Springer MA, Hansen JW, Diersen-Schade DA. J Pediatr. 2005 Apr;146(4):461-8.

Higher de novo synthesized fatty acids and lower o3- and o6-long-chain polyunsaturated fatty acids in umbilical vessels of women with preeclampsia and high fish intakes. Victor J.B. Huiskes a, Remko S. Kuipers a, Francien V. Velzing-Aarts a, D.A. Janneke Dijck-Brouwer a, Jan van der Meulen b, Frits A.J. Muskiet. Prostaglandins, Leukotrienes and Essential Fatty Acids 80 (2009) 101106 Impaired maternal glucose homeostasis during pregnancy is a.s.sociated with low status of long-chain polyunsaturated fatty acids. (LCP) and essential fatty acids (EFA) in the fetus. D.A. Janneke Dijck-Brouwera, Mijna Hadders-Algrab, Hylco Bouwstrab, Tama's Decsic, Gunther Boehmd, Ingrid A. Martinie, E. Rudy Boersmaf, Frits A.J. Muskieta. Prostaglandins, Leukotrienes and Essential Fatty Acids 73 (2005) 8587.

The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation. Stein DT, Stevenson BE, Chester MW, Basit M, Daniels MB, Turley SD, McGarry JD. J Clin Invest. 1997 Jul 15;100(2):398-403.

Intestinally derived lipids: Metabolic regulation and consequences-An overview. Katherine Cianflone,Sabina Paglialunga, Christian Roy. Atherosclerosis Supplements 9 (2008) 6368.

Determinants of serum triglycerides and high-density lipoprotein cholesterol in traditional Trobriand Islanders: the Kitava Study. Lindeberg S, Ahren B, Nilsson A, Cordain L, Nilsson-Ehle P, Vessby B. Scand J Clin Lab Invest. 2003;63(3):175-80.

A randomized trial of a low-carbohydrate diet vs orlistat plus a low-fat diet for weight loss. Yancy WS Jr, Westman EC, McDuffie JR, Grambow SC, Jeffreys AS, Bolton J, Chalecki A,Oddone EZ. Arch Intern Med. 2010 Jan 25;170(2):136-45.

A randomized trial of high-dose compared with low-dose omega-3 fatty acids in severe IgA nephropathy. Donadio JV Jr, Larson TS, Bergstralh EJ, Grande JP. J Am Soc Nephrol. 2001 Apr;12(4):791-9.

Long-chain polyunsaturated fatty acids in maternal and infant nutrition. Muskiet FA, van Goor SA, Kuipers RS, Velzing-Aarts FV, Smit EN, Bouwstra H, Dijck-Brouwer DA, Boersma ER, Hadders-Algra M. Prostaglandins Leukot Essent Fatty Acids. 2006 Sep;75(3):135-44. Epub 2006 Jul 28.

Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. Groeger AL, Cipollina C, Cole MP, Woodc.o.c.k SR, Bonacci G, Rudolph TK, Rudolph V, Freeman BA, Schopfer FJ. Nat Chem Biol. 2010 Jun;6(6):433-41. Epub 2010 May 2.

Long-chain n-3 PUFA: plant v. marine sources. Williams CM, Burdge G. Proc Nutr Soc. 2006 Feb;65(1):42-50.

Polyunsaturated fatty acid status of Dutch vegans and omnivores. Fokkema MR, Brouwer DA, Hasperhoven MB, Hettema Y, Bemelmans WJ, Muskiet FA. Prostaglandins Leukot Essent Fatty Acids. 2000 Nov;63(5):279-85.

Combined treatment with renin-angiotensin system blockers and polyunsaturated fatty acids in proteinuric IgA nephropathy: a randomized controlled trial. Ferraro PM, Ferraccioli GF, Gambaro G, Fulignati P, Costanzi S. Nephrol Dial Transplant. 2009 Jan;24(1):156-60. Epub 2008 Aug 6.

Peroxisomal retroconversion of docosahexaenoic acid (22:6(n-3)) to eicosapentaenoic acid (20:5(n-3)) studied in isolated rat liver cells. Grnn M, Christensen E, Hagve TA, Christophersen BO. Biochim Biophys Acta. 1991 Jan 4;1081(1):85-91.

Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. Fokkema MR, Brouwer DA, Hasperhoven MB, Martini IA, Muskiet FA. Prostaglandins Leukot Essent Fatty Acids. 2000 Nov;63(5):287-92.

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S,Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Naar AM. Genes Dev. 2010 Jul 1;24(13):1403-17.

The effects on plasma, red cell and platelet fatty acids of taking 12 g/day of ethyl-eicosapentaenoate for 16 months: dih.o.m.ogammalinolenic, arachidonic and docosahexaenoic acids and relevance to Inuit metabolism. Horrobin D, Fokkema MR, Muskiet FA. Prostaglandins Leukot Essent Fatty Acids. 2003 May;68(5):301-4.

Fat and fatty acid terminology, methods of a.n.a.lysis and fat digestion and metabolism: a background review paper. Ratnayake WM, Galli C. Ann Nutr Metab. 2009;55(1-3):8-43. Epub 2009 Sep 15.

Effects of fat and fatty acid intake on inflammatory and immune responses: a critical review. Galli C, Calder PC. Ann Nutr Metab. 2009;55(1-3):123-39. Epub 2009 Sep 15.

Fat intake and CNS functioning: ageing and disease. Crawford MA, Bazinet RP, Sinclair AJ. Ann Nutr Metab. 2009;55(1-3):202-28. Epub 2009 Sep 15.

Background review paper on total fat, fatty acid intake and cancers. Gerber M. Ann Nutr Metab. 2009;55(1-3):140-61. Epub 2009 Sep 15.

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. Hoehn KL, Turner N, Swarbrick MM, Wilks D, Preston E, Phua Y, Joshi H, Furler SM, Larance M,Hegarty BD, Leslie SJ, Pickford R, Hoy AJ, Kraegen EW, James DE, c.o.o.ney GJ. Cell Metab. 2010 Jan;11(1):70-6.

Dietary fat and coronary heart disease: summary of evidence from prospective cohort and randomised controlled trials. Skeaff CM, Miller J. Ann Nutr Metab. 2009;55(1-3):173-201. Epub 2009 Sep 15.

A diet rich in coconut oil reduces diurnal postprandial variations in circulating tissue plasminogen activator antigen and fasting lipoprotein (a) compared with a diet rich in unsaturated fat in women. Muller H, Lindman AS, Blomfeldt A, Seljeflot I, Pedersen JI. J Nutr. 2003 Nov;133(11):3422-7.

Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores. Conquer JA, Holub BJ. Lipids. 1997 Mar;32(3):341-5.

Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepat.i.tis. Tanaka N, Sano K, Horiuchi A, Tanaka E, Kiyosawa K, Aoyama T. J Clin Gastroenterol. 2008 Apr;42(4):413-8.

Incorporation of n-3 fatty acids into plasma lipid fractions, and erythrocyte membranes and platelets during dietary supplementation with fish, fish oil, and docosahexaenoic acid-rich oil among healthy young men. Vidgren HM, Agren JJ, Schwab U, Rissanen T, Hanninen O, Uusitupa MI. Lipids. 1997 Jul;32(7):697-705.

Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy. Stark KD, Holub BJ. Am J Clin Nutr. 2004 May;79(5):765-73.

Effects of dietary coconut oil on the biochemical and anthropometric profiles of women presenting abdominal obesity. a.s.sunco ML, Ferreira HS, dos Santos AF, Cabral CR Jr, Florencio TM. Lipids. 2009 Jul;44(7):593-601. Epub 2009 May 13.

Is body size a biomarker for optimizing dosing of omega-3 polyunsaturated fatty acids in the treatment of patients with IgA nephropathy? Donadio JV, Bergstralh EJ, Bibus DM, Grande JP. Clin J Am Soc Nephrol. 2006 Sep;1(5):933-9. Epub 2006 Aug 2.

Endothelium as an organ system. Aird WC. Crit Care Med. 2004 May;32(5 Suppl):S271-9.

Lipid lowering treatment patterns and goal attainment in Nordic patients with hyperlipidemia. Svilaas A, Strandberg T, Eriksson M, Hildebrandt P, Westheim A. Scand Cardiovasc J. 2008 Aug;42(4):279-87.

The fallacies of the lipid hypothesis. Ravnskov U. Scand Cardiovasc J. 2008 Aug;42(4):236-9.

Cholesterol does not cause coronary heart disease in contrast to stress. Rosch PJ. Scand Cardiovasc J. 2008 Aug;42(4):244-9.

End of the road for the diet-heart theory? Werko L. Scand Cardiovasc J. 2008 Aug;42(4):250-5.

-Linolenic acid does not augment long-chain polyunsaturated fatty acid -3 status. D. A. J. Brouwe, aY. Hettemaa, J. J. van Doormaalb and F. A. J. Muskieta. Prostaglandins, Leukotrienes and Essential Fatty Acids. Volume 59, Issue 5, November 1998, Pages 329-334.

Sleep Chapter Eight: Stress and Cortisol or.

Why This Book Should Be t.i.tled: Sleep Ya Big Dummy!

a.s.sociations between sleep loss and increased risk of obesity and diabetes. Knutson KL, Van Cauter E. Ann N Y Acad Sci. 2008;1129:287-304.

Sleep problems and suicidality in the National Comorbidity Survey Replication. Wojnar M, Ilgen MA, Wojnar J, McCammon RJ, Valenstein M, Brower KJ. J Psychiatr Res. 2009 Feb;43(5):526-31. Epub 2008 Sep 7.

Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. Spiegel K, Knutson K, Leproult R, Tasali E, Van Cauter E. J Appl Physiol. 2005 Nov;99(5):2008-19.

Acute partial sleep deprivation increases food intake in healthy men. Brondel L, Romer MA, Nougues PM, Touyarou P, Davenne D. Am J Clin Nutr. 2010 Jun;91(6):1550-9. Epub 2010 Mar 31.

Paradoxical sleep deprivation impairs spatial learning and affects membrane excitability and mitochondrial protein in the hippocampus. Yang RH, Hu SJ, w.a.n.g Y, Zhang WB, Luo WJ, Chen JY. Brain Res. 2008 Sep 16;1230:224-32. Epub 2008 Jul 17.

Sleep deprivation and vigilant attention. Lim J, Dinges DF. Ann N Y Acad Sci. 2008;1129:305-22.

Sleep and the epidemic of obesity in children and adults. Van Cauter E, Knutson KL. Eur J Endocrinol. 2008 Dec;159 Suppl 1:S59-66. Epub 2008 Aug 21.

A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects. Donga E, van Dijk M, van Dijk JG, Biermasz NR, Lammers GJ, van Kralingen KW, Corssmit EP,Romijn JA. J Clin Endocrinol Metab. 2010 Jun;95(6):2963-8. Epub 2010 Apr 6.

Roles of circadian rhythmicity and sleep in human glucose regulation. Van Cauter E, Polonsky KS, Scheen AJ. Endocr Rev. 1997 Oct;18(5):716-38.

Risk of breast cancer after night- and shift work: current evidence and ongoing studies in Denmark. Hansen J. Cancer Causes Control. 2006 May;17(4):531-7.

Night shift work, light at night, and risk of breast cancer. Davis S, Mirick DK, Stevens RG. J Natl Cancer Inst. 2001 Oct 17;93(20):1557-62.

Sleep deprivation impairs cAMP signalling in the hippocampus. Vecsey CG, Baillie GS, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown KM, Li XY, Descalzi G, Kim SS, Chen T, Shang YZ, Zhuo M, Houslay MD, Abel T. Nature. 2009 Oct 22;461(7267):1122-5.

Long sleep duration and childhood overweight/obesity and body fat. Padez C, Mourao I, Moreira P, Rosado V. Am J Hum Biol. 2009 May-Jun;21(3):371-6.

Epigenetics, evolution, endocrine disruption, health, and disease. Crews D, McLachlan JA. Endocrinology. 2006 Jun;147(6 Suppl):S4-10. Epub 2006 May 11.

Epigenetics and human disease. Jiang YH, Bressler J, Beaudet AL. Annu Rev Genomics Hum Genet. 2004;5:479-510.

Does sleep play a role in memory consolidation? A comparative test. Capellini I, McNamara P, Preston BT, Nunn CL, Barton RA. PLoS One. 2009;4(2):e4609. Epub 2009 Feb 25.

Influence of cortisol status on leptin secretion. Leal-Cerro A, Soto A, Martinez MA, Dieguez C, Casanueva FF. Pituitary. 2001 Jan-Apr;4(1-2):111-6.

Elevated fasting plasma cortisol is a.s.sociated with ischemic heart disease and its risk factors in people with type 2 diabetes: the Edinburgh type 2 diabetes study. Reynolds RM, Labad J, Strachan MW, Braun A, Fowkes FG, Lee AJ, Frier BM, Seckl JR, Walker BR, Price JF; J Clin Endocrinol Metab. 2010 Apr;95(4):1602-8. Epub 2010 Feb 3.

Circadian timing of food intake contributes to weight gain. Arble DM, Ba.s.s J, Laposky AD, Vitaterna MH, Turek FW. Obesity (Silver Spring). 2009 Nov;17(11):2100-2. Epub 2009 Sep 3.

Circadian disruption, shift work and the risk of cancer: a summary of the evidence and studies in Seattle. Davis S, Mirick DK. Cancer Causes Control. 2006 May;17(4):539-45.

Biological clocks and shift work: circadian dysregulation and potential long-term effects. Haus E, Smolensky M. Cancer Causes Control. 2006 May;17(4):489-500.