Disturbances of the Heart Part 21

A permanently rapid heart, when the patient has no heart lesion and is at rest, is generally due to hypersecretion of the thyroid, which will be discussed later. Paroxysmal tachycardia is a name applied to very rapid heart attacks in persons who are more or less subject to their recurrence. They may occur without any tangible excuse, and are liable to occur during serious illness, after a large meal, after a cup of tea or coffee, or after taking alcohol. The heart may beat as rapidly as from 150 to 200 times a minute, or even more, with no other symptoms than a feeling of constriction or tightness in the chest, an inability to respire properly and a feeling of "air hunger." The patient almost invariably must sit up, or at least have his head raised. Attacks of cardiac delirium (often auricular fibrillation) may occur with serious lesions of the heart, as valvular disease or sclerosis, but paroxysmal tachvcardia occurs in certain persons without any tangible cardiac excuse. The auricles of the heart may act more energetically than normal, and precede as usual the ventricular contraction; or the auricles and ventricles may contract almost together--a so-called "nodal" type of contraction. Rarely does a patient die of paroxysmal tachycardia.

The length of time the attack may last varies from a few minutes to an hour, or even for a day or more.

MANAGEMENT

There is no specific treatment for paroxysmal tachycardia. What is of value in one patient may be of no value in another; in fact, drugs are rarely successful in ameliorating or preventing the condition. Patients who are accustomed to these attacks often learn what particular position or management stops the attack.

Sometimes a patient rises and walks about. Sometimes an ice-bag over the heart will stop the attack.

If there is no serious illness present, and no serious cardiac disease causing the condition, and a patient is known to have an overloaded stomach or bowels, an emetic or a briskly acting cathartic is the best possible treatment. The attack often terminates as suddenly as it begins, without leaving any knowledge as to which particular treatment has been beneficial. A patient who is well and has an attack of tachycardia should be allowed to a.s.sume the position which he finds to give him the most comfort, and to use the means of stopping his attack which lie has found the most successful. In the absence of his success or of his knowledge of any successful treatment, a hypodermic injection of 1/6 or even 1/4 grain of morphin sulphate is often curative. Atropin should not be given, as it may increase the cardiac disturbance. If an attack lasts more than an hour or so, one of the best treatments is the bromids, which should be given either by pota.s.sium or sodium bromid in a dose of 2 or 3 gm. (30 or 45 grains) at once. Sometimes one good-sized dose of digitalis may be of benefit, but it is often disappointing, and unless there is a valvular lesion with signs of broken compensation, it is rarely indicated. It should also be remembered that, if the patient is receiving digitalis in good dosage for broken compensation, tachycardia may be caused by an overaction of the digitalis. Such overaction would be indicated by previous symptoms of nausea, vomiting, intestinal irritation, a diminished amount of urine, headache and a tight, bandlike feeling in the head, cold hands and feet, and a day or two of very slow pulse. If none of these symptoms is present, though a patient has received digitalis for broken compensation, a tachycardia occurring might not contraindicate digitalis, as much of the digitalis on the market is useless; and a patient may not actually have been obtaining digitalis action.

If the tachycardia occurs in a patient with arteriosclerosis, especially if there is much cardiac pain, nitroglycerin is of advantage; also warm foot-baths. If there is prostration and a flaccid, flabby abdomen, a tight abdominal bandage may be of benefit.

Gastric flatulence, while perhaps not a cause of the tachycardia, is liable to develop and be a troublesome symptom. Anything that causes eructations of gases is of benefit, as spirit of peppermint, aromatic spirit of ammonia or plain hot water. If there is hyperacidity of the stomach, sodium bicarbonate or milk of magnesia will be of benefit.

The ability of some patients to stand a rapid heart action without noting it or being incapacitated by it is astonishing. It may generally be stated that a rapid heart is noted, and a pulse above 120 generally prostrates, at least temporarily, a patient who is otherwise well, provided the cause is anything but hyperthyroidism.

A patient who has hypersecretion of the thyroid will be perfectly calm, collected, often perhaps not seriously nervous, and, with a heart beating at the rate of 140, 150, 160 and even 200 per minute, will state that she has no palpitation now, although she sometimes has it. A heart thus fast, with a patient not noting it and not prostrated by it, is almost diagnostic of a thyroid cause.

Some patients, both men and women, cannot take even a small cup of tea or coffee without an attack of paroxysmal tachycardia. Such patients, of course, quickly learn their limitations.

HYPERTHYROIDISM

The presence of a well marked case of exophthalmic goiter is not necessary for the secretion of the thyroid to be increased sufficiently to cause tachycardia; in fact, an increased heart rapidity in women often has hyperthyroidism as its cause. The thyroid gland hypersecretes in women before every menstrual period and during each pregnancy, and with an active, emotional, nervous life, social excitement, theaters, too much coffee, and, unfortunately today among women, too much alcohol, it readily gives the condition of increased secretion; and the organ that notes this increased secretion the quickest is the heart.

The tachycardia of a developed exophthalmic goiter is difficult to inhibit. Digitalis is of no avail, and no other single medicinal treatment is of any great value. The tachycardia will improve as the disease improves. On the other hand, nothing is snore serious for this patient than her rapid heart, and if it cannot be soon slowed, operative interference is absolutely necessary. If the rapid heart continues until a myocarditis has developed and a weakening of the muscle fibers occurs, or dilatation is imminent or has actually occurred, operative interference is serious, and most patients under these conditions die after a complete operation, that is, the removal of from one half to two thirds of the thyroid. In such cases the only excusable operative interference is the graded one, namely, the tying of first one artery and then another of the thyroid to inhibit the blood supply to the gland in order that it may not furnish so much secretion. If the heart then improves, a more radical operation may be done without much serious danger. Therefore the working rule should be that, if a heart does not quickly improve under medical management, operative interference should not be delayed until the heart has become degenerated.

If tachycardia is the only serious symptom present in a patient who is considered to have hyperthyroidism, it may generally be successfully treated by insistence on quiet, cessation of all physical and exciting mental activities, more or less complete rest, the absolute interdiction of all tear coffee or other caffein- bearing preparations, total abstinence from alcohol, the restriction to a cereal and fruit diet (the withdrawal of all meat from the diet), the administration of calcium, as the calcium glycerophospate in dose of 0.3 gm. (5 grains) in powder three times a day, and for a time, perhaps, the administration of bromids. If the depressing action of bromids on the heart is counteracted by the coincident administration of digitalis, they will act only for good by quieting the nervous system and more or less inhibiting the secretion of the thyroid gland.

If a patient has exophthalmic goiter fully developed, absolute rest in bed, with the treatment outlined above, should soon cause improvement. If it does not, the operative treatment as advised above should be considered. If myocarditis has been diagnosed, the minor operations should be done if the patient does not soon improve. The prolongation of the treatment depends on the condition and the amount of improvement.

If the physician is in doubt as to whether or not this particular tachycardia is caused by hyperthyroidism, the administration of sodium iodid in doses of 0.25 gm. (4 grains) three times a day will make the diagnosis positive within a few days. If the trouble is due to hyperthyroidism, all of the symptoms will be aggravated; there will be more palpitation, more nervousness, more restlessness, more sweating and more sleeplessness. In such cases the iodid should be stopped immediately, of course, and the proper treatment begun.

TOXIC DISTURBANCES AND HEART RATE

Under this head it is not proposed to consider disturbances of the heart due to infections, to cardiac disease, or to localized or general acute or chronic disease, but to discuss disturbances due to the absorption of irritants froth the intestines, and to alcohol, tobacco and caffein.

It is hardly necessary to repeat that various toxins which may seriously irritate the heart may be absorbed from the intestines during fermentation or putrefactives processes in either the small or the large intestines. The heart may be slowed by some, made rapid by others, and it is often made irregular. The relation of the absorption of intestinal toxins to increased blood pressure has already been described, and the necessity of removing from the diet anything which perpetuates or increases intestinal indigestion in all cases of high blood pressure has already been referred to several times. The indications that such a condition of the intestines is present are irregular action of the bowels, a large amount of intestinal gas, sometimes watery stools, often a coated tongue, and the presence of indican in the urine.

INTESTINAL PUTREFACTION

The most successful procedure in the management of intestinal putrefaction is to remove meat from the diet absolutely. Laxatives in some form are generally indicated, and one of tile best is agar- agar. Of course aloin and cascara are always good laxatives, with an occasional dose of calomel or saline, if such seem indicated. Some of the solid hydrogen peroxid-carrying preparations (magnesium peroxid, calcium peroxide [Footnote: See N. N. R., 1916, p. 232]) have been advised as bowel antiseptics, but they are not more successful than many of the salicylic acid preparations,' and perhaps none is more efficient than salol (phenyl salicylate) in a dose of 0.3 gm. (5 grains), three or four times a day. Washing out the colon with high injections is often of great value, but should not be continued too long lest the r.e.c.t.u.m become habituated to distention, and bowel movements not take place without an enema.

Lactic acid bacilli, best the Bulgarian, arc often of value in intestinal fermentation. A tablet may be eaten with a little lactose or a small lump of sucrose after each meal. Or yeast may be taken in the forth of brewer's yeast, a tablespoonful in a gla.s.s of water, two or three times a day, or one sixth of an ordinary compressed yeast cake dissolved is a gla.s.s of 'eater and taken once or twice a day. Or various forms of lactic acid fermented milk may be successful.

Any particular food which causes fermentation in the intestine of the patient should be eliminated from his diet; the patient must be individualized as to fruits, cereals and vegetables, Nit, as stated above, meat should ordinarily be withheld for a time at least.

ALCOHOL

Enough has already been said of the value and limitations of alcohol as a therapeutic agent. As a beverage, when constantly used, it is liable to cause obesity, gastric indigestion, arteriosclerosis, myocardial degeneration, chronic nephritis and cirrhosis of the liver. Its first action is undoubtedly as a food, if not too large amounts are taken, and therefore it is a protector of other food, especially of fat and starch. A habitue, then, especially if he has reached the age at which he normally adds weight, increases his tendency to obesity, and the first mistake in his nutrition is made.

If lie takes too much alcohol when he eats or afterward, his digestion will be interfered with. Sooner or later, then, gastritis and stomach indigestion develop, with consequent intestinal indigestion. If lie takes strong alcohol, like whisky, oil an empty stomach, he may sooner or later cause serious disease of the mucous membrane of the stomach, first chronic gastritis, and later atrophy of the glands of the stomach.

Alcohol with meals which contain meat tends to the production of an increased amount of uric acid. Alcohol taken before meals on an empty stomach causes sudden vasodilatation after absorption. It goes quickly to the liver, irritates it, and little by little causes congestions of the liver, so that sooner or later sclerosis of this organ develops.

Alcohol probably causes arteriosclerosis not by its action per se, but indirectly by causing gastro-intestinal indigestion and insufficiency of the liver, as a result of which more toxins circulate in the blood, tending to produce arteriosclerosis. Sooner or later these irritants cause kidney irritation, and chronic interst.i.tial nephritis may develop. just which process becomes the farthest advanced and finally kills the patient is an individual proposition and cannot be foretold. The finale may be cirrhosis of the liver, uremia, arteriosclerosis, apoplexy or myocarditis with dilatation or coronary disease.

While small, more or less undiluted closes of alcohol, as whisky or brandy, may cause quick stimulation of the heart by reflex irritation of the esophagus and stomach, vasodilatation occurs as soon as the alcohol is absorbed, and if large closes are absorbed, vasomotor paresis may occur, temporarily at least.

During acute fever processes with an increased pulse rate, provided shock or collapse is not present, small or medium-sized doses of alcohol, by dilating the peripheral blood vessels and increasing the peripheral circulation, may relieve the tension of the heart and slow the pulse by the equalization of the circulation. Some of this action may be due to the narcotic effect of alcohol on the cerebrum.

Alcohol may thus in many instances act for good. Overdoses, as shown by cerebral excitation, flushing of the face and increased pulse rate, will do harm; in fact, many a patient with a serious illness, as typhoid fever or pneumonia, is made delirious by alcohol. Large doses of alcohol in shock or collapse are contraindicated.

Chronic overuse of alcohol may cause chronic myocarditis and fatty degeneration of the heart, with later weakening of the heart muscle and dilatation.

In acute alcohol poisoning the pulse may become very rapid and weak, and the patient may die of heart failure. This is often seen in delirium tremens. The administration in this condition of enormous doses of digitalis by the stomach is inexcusable, and the reason that such patients survive such digitalis poisoning is that the stomach does not absorb during this cardiac prostration.

A treatment as successful as any in this heart weakness in delirium tremens is morphin sulphate, 1/2 grain, and atropin, 1/15 grain, given hypodermically, with the administration of digitalis hypodermically for its later action on the heart. If the heart is contracting very rapidly, an ice-bag over the precordia will often quiet it. If the pulse is very weak, the cerebral sedatives more frequently used in delirium tremens, such as chloral, bromids, paraldehyd, etc., are generally contraindicated. A hot foot-bath and an ice-cap on the head sometimes aid in establishing a more general equalization of the circulation. It may often be necessary to administer strychnin, although if the patient is greatly excited it should be withheld as long as possible. For the same reason camphor, coffee and other cardiac stimulants which cause cerebral excitation should be withheld.

If the patient is in alcoholic coma, the pulse is generally slow, although it may be of low pressure unless the patient is otherwise diseased. Caffein or coffee is here indicated, and the patient should be kept warm lest he lose necessary heat. The stomach should be emptied by an emetic, often best by apomorphin hypodermically, unless the pulse is excessively weak. Strychnin may also be given, and digitalis, hypodermically, if it seems indicated. Camphor is another cardiac and cerebral stimulant that is valuable in these cases.

The treatment of an actual degeneration of the heart from overuse of alcohol is similar to the sane condition from other causes.

CAFFEIN

Caffein can irritate the heart and cause irregularity and tachycardia, especially in certain persons. In fact, some can never take a single cup of coffee without having an attack of palpitation, and many times when coffee and tea have been unsuspected by the patient as the cause of cardiac irritability, their removal from the diet has stopped the symptoms, and the heart has at once acted normally.

Caffein is a stimulant and tonic to the heart, increasing its rapidity and the strength of the contractions. It is also a cerebral stimulant, one of the most active that we possess among the drugs.

It increases the blood pressure, princ.i.p.ally by stimulating the vasomotor center and by increasing the heart strength. It acts as a diuretic, not only by increasing the circulatory force and blood pressure, but also by acting directly on the kidney. This action on the kidney contraindicates the use of caffein in any form, except in rare instances, when there is acute or chronic nephritis. The increased blood pressure caused by caffein also contraindicates its use when there is hypertension. Caffein first accelerates the heart and later may slow it and strengthen it; but if the dose is large or too frequently repeated, the apex of the heart ceases to relax properly and there is an interference with the contraction of the ventricles, the heart muscle becomes irritable, and a tachycardia may develop.

Therefore when a heart has serious lesions, whether of the myocardium or of the valves, with compensation only sufficient, the action of caffein in any form is contraindicated. The fact that it raises the blood pressure, thus increasing the force against which the heart must act, and that it irritates the heart muscle to more st.u.r.dy or irregular contraction, indicates that a patient with a heart lesion or with a nervously irritable heart should never drink tea and coffee or take caffein in any beverage.

Many patients cannot sleep for many hours after they have taken coffee or tea, as the cerebral stimulation of caffein is projected for hours after its ingestion. Caffein does not absorb so quickly and therefore does not act so quickly when taken in the form of tea and coffee as it does when taken as the drug or as a beverage which contains the alkaloid. Persons who are nervously irritable, excited and overstimulated cerebrally, with or without high blood pressure, should not take this cerebral and nervous excitant. This is true in early childhood and in youth, and continues true as age advances, in most persons. It is a crime to present caffein as a soda fountain beverage to children and young persons when the excitement of the age is such as already to overstimulate all nervous systems and all hearts.

A considerable majority of persons over 40 learn that they cannot drink tea or coffee with their evening meal without finding it difficult to sleep. Such patients, of course, should omit this stimulant. Some patients have already recognized this fact and its cause; others must be told. The majority of adults are probably no worse and may be distinctly benefited by the morning cup of coffee and the noon coffee or tea, provided the amount taken is not large.

It seems to be a fact that the drinking of coffee is on the increase, especially as to frequency. Certainly the five o'clock tea, with women, is on the increase, and we must deal with one more cerebral and nervous excitant in our consideration of what we shall do to slow this rapid age.

TOBACCO

In spite of the fact that a large number of men today do not smoke, more and more frequently every clinician has a patient who smokes too much. The accuracy with which he investigates these cases depends somewhat on his personal use of tobacco, and therefore his leniency toward a fellow user. Perhaps the percentage of young boys who smoke excessively is larger than the percentage of men. Whether or not the term "excessive" should be applied to any particular amount of tobacco consumed depends entirely on the person. What may be only a large amount for one person may be an excessive amount for another, and even one cigar a day may be too much for a person is as much for him as five or more cigars for another. If one is to judge by the internal revenue report it will appear that, in spite of the public school instruction as to the physiologic action of tobacco and its harm, and in spite of the ant.i.tobacco leagues, the consumption of tobacco is enormously on the increase.

Alexander Lambert [Footnote: Lambert, Alexander: Med. Rec., New York, Feb. 13, 1915] in studying periodic drinkers and alcoholics, finds that most patients are suffering from chronic tobacco poisoning, and if they stop their smoking, their drinking sometimes ceases automatically.